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- Ugly (unpleasant in appearance or manner)
- Ulcerated (infected, deteriorating)
- Ultimate (when used negatively to mean extreme in a bad way)
- Unabashed (shamelessly bold in a bad way)
- Unacceptable (not good enough, intolerable)
- Unaccomplished (lacking achievements)
- Unaccountable (irresponsible, not taking responsibility)
- Unachievable (impossible to reach)
- Unadaptable (unable to adjust)
- Unaffordable (too expensive, out of reach)
- Unappealing (not attractive or interesting)
- Unappreciative (not grateful, lacking gratitude)
- Unapproachable (distant, unfriendly)
- Unapproved (not accepted, rejected)
- Unarmed (vulnerable, defenseless)
- Unashamed (lacking remorse for bad actions)
- Unattractive (not pleasing to look at)
- Unauthentic (fake, lacking genuineness)
- Unavailable (not present, absent)
- Unbearable (too painful or annoying to handle)
- Unbecoming (inappropriate, not suitable)
- Unbelievable (too extreme to be true, unrealistic)
- Unbending (stubborn, inflexible)
- Uncaring (lacking compassion)
- Uncertain (unsure, not clear)
- Unchangeable (stuck, unable to improve)
- Uncharitable (harsh, unkind)
- Unclean (dirty, impure)
- Unclear (not understandable)
- Uncomfortable (causing unease or distress)
- Uncommunicative (not willing to talk)
- Uncompassionate (lacking empathy)
- Uncompromising (rigid, unwilling to change)
- Unconcerned (not caring, indifferent)
- Unconscious (unaware, not alert)
- Uncontrollable (out of control, chaotic)
- Uncooperative (not helpful, refusing to assist)
- Unconvincing (not persuasive, weak argument)
- Uncool (not stylish, socially awkward)
- Uncreative (lacking imagination)
- Uncultured (lacking manners or refinement)
- Undecided (unable to make choices)
- Undependable (not reliable)
- Undesirable (not wanted, unpleasant)
- Undignified (lacking respectability)
- Uneasy (anxious, nervous)
- Uneconomical (wasteful, not cost-effective)
- Uneducated (lacking knowledge or schooling)
- Unemotional (lacking feeling)
- Unenjoyable (not fun, unpleasant)
- Unequal (unfair, unjust)
- Uneven (not balanced, inconsistent)
- Unethical (dishonest, immoral)
- Unfair (biased, unjust)
- Unfaithful (disloyal, untrustworthy)
- Unfamiliar (strange, unknown)
- Unfashionable (outdated, unstylish)
- Unfeeling (emotionless, cold)
- Unfit (not suitable, unhealthy)
- Unforgiving (harsh, unwilling to forgive)
- Unfortunate (bad luck, unlucky)
- Unfriendly (cold, rude)
- Unfulfilled (not satisfied, disappointed)
- Unfunny (not humorous)
- Ungrateful (lacking appreciation)
- Unhappy (sad, dissatisfied)
- Unhealthy (not physically or mentally well)
- Unhelpful (not useful)
- Unimaginative (lacking creativity)
- Unimportant (not significant)
- Uninformed (lacking knowledge)
- Unintelligent (not smart)
- Uninteresting (boring, dull)
- Uninviting (not welcoming)
- Unjust (not fair, morally wrong)
- Unkind (mean, cruel)
- Unlawful (illegal, against the rules)
- Unlikable (not pleasant, hard to get along with)
- Unlucky (having bad fortune)
- Unmotivated (lacking drive or ambition)
- Unnatural (forced, not genuine)
- Unnecessary (not needed, excessive)
- Unpleasant (not enjoyable)
- Unpredictable (difficult to anticipate, unstable)
- Unproductive (not getting anything done)
- Unprofessional (not behaving appropriately)
- Unreliable (not trustworthy)
- Unresponsive (not reacting, ignoring)
- Unruly (disruptive, not following rules)
- Unsafe (dangerous, risky)
- Unsanitary (dirty, unhygienic)
- Unsettling (disturbing, causing discomfort)
- Unsightly (ugly, unattractive)
- Unsociable (not friendly, avoiding people)
- Unsophisticated (lacking refinement or knowledge)
- Unstable (not steady, mentally or physically weak)
- Unsuccessful (failing to achieve goals)
- Unsure (lacking confidence, uncertain)
- Untrustworthy (not reliable, dishonest)
- Unwanted (not desired, rejected)
- Unwelcome (not invited, rejected)
- Unwise (not smart, making poor decisions)
- Unworthy (not deserving, lacking value)
