- Quacky (untrustworthy, like a fake doctor or scam)
- Quagmired (stuck in a difficult or hopeless situation)
- Quaking (shaking with fear or weakness)
- Quarrelsome (always arguing or fighting)
- Queasy (feeling sick or uneasy)
- Querulous (complaining or whining a lot)
- Questionable (doubtful, not trustworthy)
- Quibbling (arguing over small or unimportant things)
- Quirky (when used negatively to mean odd or off-putting)
- Quixotic (impractical or unrealistic in a foolish way)
- Quizzical (when referring to confusion or skepticism)
- Quenched (when enthusiasm or excitement is extinguished)
- Quivering (shaking with fear, weakness, or nervousness)
- Quashed (crushed, suppressed, or forcefully ended)
- Qualmish (having doubts, uneasy, or feeling sick)
- Quasi-competent (barely capable, but not good enough)
- Quiescent (inactive in a way that suggests laziness or uselessness)
- Quicksand-like (unstable, dangerous, or unreliable)
- Quirksome (annoyingly odd or eccentric)
- Quavering (trembling or weak-sounding, often from fear)
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